Research of the Day – Nov 12, 2012 – Fish oil can help your liver… but it isn’t magical

Hey Folks!

Research of the Day time! Todays research is brought to you by my homework as well as the fact that I got a bunch of fish oil in at the office last week and am hoping to dish it out to whoever needs the best fish oil money can buy! Great price too – but if you’d prefer not to buy from me, that’s fine too, I’ll get through them all myself eventually otherwise.

Todays article:

Omega-3 fatty acids for the treatment of non-alcoholic fatty liver disease

What they did:

  • Reviewed they literature regarding the use of Omega 3 fatty acids in the management of non-alcoholic fatty liver disease (NAFLD)

What they reported:

  • Omega 3 fats EPA and DHA are associated with greater oxidation of fat (using it for enegy) in the liver… meaning less accumulation.
  • Reduced inflammatory markers and increased non-inflammatory markers in the liver
  • They inhibited liver glycolysis and lipogenesis by reducing the expression of genes involved with activating those pathways (YOU MEAN THE ENVIRONMENT AFFECTED THE GENES???)
  • Diets high in cholesterol, sucrose or fructose fed to mice eventually led to NAFLD
  • They tested rats with deficiency of Omega 3 fatty acids for NAFLD, which they developed (along with insulin resistance), and then treated them with omega 3’s and they got better
  • They found when they changed their diet to a high fat diet with omega 3s they halted or REVERSED their NAFLD.
  • This even worked when the rats were leptin resistant too (a hormone that tells you when you’re satisfied AKA had enough food)
  • Omega 3 fats made the rats livers more resilient to injury then those rats without an omega 3 sufficient diet
  • Insulin sensitivity went up, inflammatory cytokines went down.

What does it mean???

  • It means fish oils are good for you. Especially if you’re deficient in them (like pretty much all of us are).
  • They increase insulin sensitivity (possibly by increasing cell membrane fluidity and by modulating gene expression)
  • They reduce inflammatory cytokines, which means less unnecessary inflammation.
  • They aren’t magic. You can’t cover up poop with perfume, so don’t take studies like these the wrong way and assume fish oil is the cure-all of the century. You still can’t eat like crap and just have some fish oil to fix it. Sorry.
  • You still need to exercise, sleep well, eat well, get your spine adjusted and take some vitamin D and fish oil to round out any deficiencies you may have. It just makes sense to create sufficiency where deficiency exists.

Have at it! If you’d like some fish oil from me, let me know – it’s in the office!

Stay healthy friends!

Dr. Adam Ball